By Hiroshi Mitsumoto MD
This crucial publication covers each element of dwelling with ALS, from medical positive aspects of the illness to an outline of symptom administration to realizing its prognosis. significant sections care for overseeing remedy and rehabilitation, residing with ALS, the disease’s complex part, end-of-life concerns, and assets. greatly revised and rewritten, this variation comprises new chapters at the most recent ways to treating ALS signs, using noninvasive ventilators, multidisciplinary crew care, new guidance being constructed through the yankee Academy of Neurology for sufferers with ALS, using riluzole (Rilutek), and extra.
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Additional resources for Amyotrophic Lateral Sclerosis: A Guide for Patients and Families
Ferrebee JW, Klingman WO, Frantz AM. Vitamin E and vitamin B6. Clinical experience in the treatment of muscular dystrophy and amyotrophic lateral sclerosis. JAMA. 1941;116:1895. 66. Gurney ME, Cutting FB, Zhai P, et al. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann Neurol. 1996;39:147– 157. 67. Ascherio A, Weisskopf MG, O’Reilly EJ, et al. Vitamin E intake and risk of amyotrophic lateral sclerosis. Ann Neurol. 2005;57:104–110.
When muscles become totally paralyzed or atrophied, hyperreflexia that developed earlier in the course of the disease may disappear. In some situations, a pathologic hyperreflexia may occur in wasted muscles, a unique paradox in ALS. Muscle Hypotonicity or Flaccidity Hypotonicity or flaccidity refers to the decrease or complete loss of normal muscle resistance to passive movements. In contrast to spasticity, the muscle lies inert and floppy when passively manipulated. 32 Amyotrophic Lateral Sclerosis Fasciculations Fasciculations are fine, rapid, flickering, and sometimes vermicular (worm-like) twitching of a portion of the muscle.
Gurney ME, Cutting FB, Zhai P, et al. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann Neurol. 1996;39:147– 157. 67. Ascherio A, Weisskopf MG, O’Reilly EJ, et al. Vitamin E intake and risk of amyotrophic lateral sclerosis. Ann Neurol. 2005;57:104–110. 68. Bensimon G, Lacomblez L, Meininger V. A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. N Engl J Med. 1994;330:585–591. 69. Miller RG, Moore D, Young LA, et al.
Amyotrophic Lateral Sclerosis: A Guide for Patients and Families by Hiroshi Mitsumoto MD